(05-21-2020, 07:08 PM)BeReel1010 Wrote: Absolutely- wasn’t sure if I could post the link but Preprints are the ones who published the study.
Thank you - interesting reading. If you want to post a link but obscure it a bit you can always get the URL and deliberately scramble the start a bit so
https://www.website.com becomes hxxps://www.website.com - although it doesn't make for such a handy clickable link! Anyway I printed the article because I'm old fashioned and can't critically evaluate science from a screen - I need it on paper :-)
This research is at an incredibly early stage - it is too early to say whether there is anything to it or not. It is years away from being a marketable product. Who knows what the results would look like when tested on humans. Also I'm a bit worried by the statistics. It is really complicated to explain, but if anyone wants to discuss p-values with me then that's fine - I'm more than 95% sure you won't (geeky stats joke).
The broader caveat I'd put on this research is that they get these varying results and (rightly) point out that medical cannabis can't be treated as generic. To start testing on people they'd need something
much more standardized. It doesn't seem to be the case that just any medical cannabis will work, which is obviously a shame for people in this forum who wish to take matters into their own hands.
Note the affiliations of all the researchers - they all work for Pathway and their business model is finding medical uses for cannabis. That doesn't nullify anything and they've honestly declared it in the paper. My concern is whether they are looking at things through the lens of "how can we make cannabis relevant to COVID-19?" rather than "out of all the drugs we know of, what modulates ACE2 receptors?". I guess what I'm questioning is whether they've started from a very narrow perspective.
I don't want to shoot them down, there could be something to it eventually. This COVID-19 pandemic is taking so many lives, people losing jobs, etc that I think we need to throw everything we have at it. So even though this specific piece of research doesn't fill me with optimism, I'm still glad they did the work. There will be a cure, the only question is when. For now I'm placing my bets on vitamin D to lessen the virus.