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10 Most Unethical Experiments Performed on Humans
#1
10. Testicular Experiments on Prisoners

Between 1913 and 1951, San Quentin Prison’s
chief surgeon, Dr. Leo Stanley, conducted
numerous testicular experiments on inmates. Among the goals of his experiments was to
determine if various manipulations on the
testicles of men would produce desired results,
including the rejuvenation of old men, the
limitation of criminal behavior, and the
prevention of reproduction by those deemed “unfit to be parents.”

One of the experiments involved the removal of testicles from healthy prisoners who had been executed, and the implantation of these
testicles into senile prisoners. The hope was
that the senile prisoners would display
improved mental health. Surprisingly, Stanley claimed the experiment a success, one 72-year- old reportedly emerging from advanced senility to display youthful “jazz and pep.”

Yet another study entailed implanting the
testicles of goats, rams, and boars into inmates. However, the procedures proved unsatisfactory when the implanted testicles ended up being rejected by the inmates’ bodies, so Stanley instead mashed the animal testicles “to the consistency of toothpaste,” then injected the substance into patients’ abdomens.

Again, the doctor reported that the injections resulted in renewed virility in the subjects.


9. Negative Speech Therapy on Children

There’s a reason this experiment is commonly
referred to as The Monster Study. In 1939, graduate student Mary Tudor, supervised by
her University of Iowa professor Wendell
Johnson, secretly made use of 22 children from an orphanage for an experiment on stuttering.

The subjects, 10 of whom had previously been
identified as stutterers, were divided into two groups, each with 5 stutterers and 6 regular
speakers. The children in the first group,
including the 5 stutterers, were told that their
speech was fine. Meanwhile, those in the
second group, including the 5 children whose
speech was fine, were told that they were stutterers whose speech behavior had to be
corrected. In the end, the results of the study
proved inconclusive.

But disturbingly, most of the non-stutterers who were told that they suffered from a speech defect ended up displaying various speech-related problems, including markedly worse performance in school and a tendency to be withdrawn.

In fact, in 2007, 68 years after the questionable experiment, the State of Iowa awarded six of the children a total of $925,000 for their psychological suffering.

8. Spraying bacteria over cities

During the 1950s, the U.S. government sprayed bacteria over entire cities, not as actual biological warfare, but as simulations of
biological attacks to prepare for such
eventualities. One such experiment took place over the city of San Francisco in 1950. In the
study, cultures of Serratia marcesens, a type of
rust-colored bacterium previously believed to be harmless to humans, were sprayed via a boat to understand how these would be dispersed.

Unfortunately, the experiment seemed to turn out much more realistically than hoped as
eleven Stanford University Hospital patients
actually developed Serratia infections, one of
the patients ending up dead. A case filed in
relation to the incident resulted in the suit being dismissed as the judge determined that the government had exercised due discretion in its experiment.

7. secret experiments on children

From 1955 to 1960, the Sonoma State Hospital
in California conducted various secret experiments on children with cerebral palsy.

The studies were uncovered by Karen
Alves, a sister of one of the experiments’
deceased subjects, after President Clinton had
ordered the declassification of documents
relating to human radiation experiments. One of those documents showed that Karen’s cerebral palsied brother, Mark, had been included in a study where patients were made to undergo extremely painful procedures, including the injection of air into the patients’ brains.

Furthermore, Mark’s medical records showed
that before the 6-year-old boy died in 1961, he had suffered from seizures, swollen eyes, and
extremely high fevers — symptoms consistent
with radiation poisoning.

6. Skin Testing on Prisoners

The late Dr. Albert Kligman is fondly
remembered for having invented Retin-A, the popular acne medication, but his legacy is also
unfortunately stained by allegations that several experiments he conducted in the Holmesburg Prison in Philadelphia were unethical.

Kligman was invited to the facility in 1951, when inmates were suffering from an athlete’s foot
outbreak, and the dermatologist quickly grabbed the opportunity to turn the prison into a product-testing laboratory.

The experiments, involving deodorants, skin creams, and hair products, among others, seemed harmless, but congressional hearings and national publicity later revealed that mind-altering drugs, radioactive substances, and various pathogens were also tested on paid prisoners.

A case filed by hundreds of former inmates in 2000 failed to prosper because the statute of limitations was found to have expired.

5. Developing Trauma in Children

The Little Albert experiment, conducted by John Hopkins University professor John
Watson and his student Rosalie
Rayner, intended to prove two theories:

(1) that fear itself was innate, rather than
conditioned, and

(2) that a child could be conditioned to fear particular things.

The subject of the experiment was Douglas Merritte, whom a 2010 study revealed was the baby of wet nurse Arvilla Merritte. In the Little Albert experiment, the 9-month-old was first exposed to various animals (a rabbit, a rat, a dog, a monkey) and objects (masks, cotton, wool, and burning newspapers, among others), and Little Albert displayed no fear of the stimuli. Then, a loud clanging sound (the innately feared stimulus) was introduced the next time the baby touched the rat, causing the child to cry. Later, when only the rat was presented without the sound, Little Albert cried and tried to move away from the animal, thus seeming to prove that he had been conditioned to fear the rat.

For obvious reasons, the experiment is today
considered ethically unacceptable.

4. Injecting Cancer Cell in Prisoners

In the 1950s, immunology expert Chester
Southam wanted to find out if cancer was contagious, so he injected over a hundred volunteer prisoners at the Ohio State
Penitentiary with cancer cells.

As he had theorized, the inmates subsequently developed tumors. Next, the scientist wanted to determine if cancer patients would be affected any differently by such injections.

He conducted the experiment at Brooklyn’s Jewish Chronic Disease Hospital. Disturbingly, Southam didn’t tell patients that they were being injected with cancer cells, and instead made them believe they were receiving human cells grown in test tubes.

Later, some doctors at the hospital exposed Southam’s misdeeds, and he was punished with one year of probation.

Nevertheless, just a few years later, the
American Association for Cancer Research
elected Southam as its president.


3. Radioactive Iodine Injections

The United States Atomic Energy Commission
(AEC) is responsible for conducting numerous
radiation experiments that are today
condemned as being grossly unethical.

Among these experiments were two 1953 studies in the University of Iowa, where newborns and pregnant women were exposed to radioactive iodine.

The first one involved exposing pregnant women to radioactive iodine, then studying their aborted embryos in order to understand the way the way the radiation affected pregnancy.

The second entailed administering, orally or through injection, radioactive iodine to 25 newborns in order to measure the accumulated iodine in the babies’ thyroid glands.
Not surprisingly, the AEC was abolished in 1974 after it suffered from widespread criticism.

2. Blood Flow and Blood Pressure Tests

In the 1960s, the Department of Pediatrics of the University of California conducted a study on blood flow and blood pressure changes in
infants aged one hour to three days.

Despite the noble objectives of the endeavor, the methods used by the scientists on the 113
newborn babies were disturbingly crude.

First, a catheter was inserted into each child’s umbilical artery until the instrument reached the aorta.

Then, the infants’ feet were immersed in ice-
cold water to quickly lower the children’s
temperatures, after which the aortic pressure
created by the immersion was measured.

Furthermore, 50 of the subjects were strapped unto a circumcision board, which was
afterwards tilted, so that blood rushed into the
infants’ heads.
The resulting blood flow and blood pressure changes were then measured.


1. Syphilis Left Untreated

In 1932, the U.S. Public Health Service, in
collaboration with the Tuskegee Institute, began a study to determine the natural progression of syphilis when left untreated.

600 poor sharecroppers from Alabama, 399 of whom had previously contracted syphilis, were selected as subjects for the study. While the experiment certainly possessed scientific merit, those responsible for the study shockingly lied to the subjects by telling them that they were being treated, when in truth, they were not.

Worse, the subjects were discouraged from seeking treatment for their disease elsewhere. In fact, even after 1940, when penicillin had been accepted as the treatment of choice for syphilis, the subjects were still not administered the drug.

It was only when the story went to press
and sparked widespread outrage in 1972 that
the study was finally terminated.

Subsequently, in 1974, a class action suit filed by the NAACP resulted in an out-of-court settlement worth $10 million.
Semper Fidelis

[Image: SyAa0qj.png]

USMC
Nemo me impune lacessit
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