Hey Raven and Jmoney12345,
Honestly, bio is absolutely correct for the most part except the complete disassociation between molecular makeup. I personally prefer diaz/alp and the only problem that presents is during one of my tapers (I've mentioned that either here or in another thread; I use the Ashton method to keep my tolerance low and have done so successfully for years). The semi regular switching between the two drives both tolerances up simultaneously thus making it a bitch to taper from diaz with diaz.
Theres always going to be an overlap in fill-in benzos and tolerance, particularly with the specific sub categories. If you take, say, triazoLAM then switch to alprazoLAM, there's going to be virtually identical tolerance raises. LorazePAM to clonazePAM will do the same. For an example, Xanax vs Klonopin. Xanax is a triazolo benzodiazepine. Klonopin is generally known as a plain old benzo, although it technically belongs to another sub family generally and informally called 7-nitro benzodiazepines. So there is some overlap when alternating those, yes, but not a lot. This is why a lot of doctors beginning treatment for GAD will prescribe alp/clon concurrently.
Long story short, there will be some tolerance crossover but not a whole hell of a lot.
There are other sub groups but I'm not totally familiar with but don't recommend like etizolam. That is a thienotriazolodiazepine and from what I understand extremely addictive when compared to most benzos, even more so than alp.
Analog drugs can be helpful for some but again, I don't recommend these. Dependence can build quickly or not at all. Some people are helped, some are. Some develop a cross tolerance, others don't. Too many variables. Clorazepate (Tranxene is an example here.)
As an interesting aside, some drugs prescribed for anxiety have some rather pleasant side effects on occasion. "Classical" benzos are usually great for off-label things. I was prescribed Chlordiazepoxide (Librium) for my anxiety for a short period and it helped me get back on my feet after a bout of SEVERE depression and OCD better than my SSRI ever hoped to. Not the same for everyone, obviously, but I foind it interesting. Librium can also help with a taper like diazepam but it's not nearly as well documented as the Ashton method so I wouldn't recommend that without a doctors help.
So anyway, yep. If you ever want to come off of benzos, ask your doctor about a diazepam or Librium taper, THANK YOU BIO FOR FIELDING THE QUESTIONS FOR ME! And yes, theres a chance your tolerance will raise switching. Not a lot but slightly. Not enough to let it stop you but enough so that you should keep close track to make sure you're not spiraling out of control. I suppose that's true in any scenario, though.
Oh, one last thing. Apologies for taking a while to respond, like I said I'm usually able to respond in less than 12 hours but yesterday was a 14 hour day so I didn't have much opportunity to get online. Thanks everyone!
Honestly, bio is absolutely correct for the most part except the complete disassociation between molecular makeup. I personally prefer diaz/alp and the only problem that presents is during one of my tapers (I've mentioned that either here or in another thread; I use the Ashton method to keep my tolerance low and have done so successfully for years). The semi regular switching between the two drives both tolerances up simultaneously thus making it a bitch to taper from diaz with diaz.
Theres always going to be an overlap in fill-in benzos and tolerance, particularly with the specific sub categories. If you take, say, triazoLAM then switch to alprazoLAM, there's going to be virtually identical tolerance raises. LorazePAM to clonazePAM will do the same. For an example, Xanax vs Klonopin. Xanax is a triazolo benzodiazepine. Klonopin is generally known as a plain old benzo, although it technically belongs to another sub family generally and informally called 7-nitro benzodiazepines. So there is some overlap when alternating those, yes, but not a lot. This is why a lot of doctors beginning treatment for GAD will prescribe alp/clon concurrently.
Long story short, there will be some tolerance crossover but not a whole hell of a lot.
There are other sub groups but I'm not totally familiar with but don't recommend like etizolam. That is a thienotriazolodiazepine and from what I understand extremely addictive when compared to most benzos, even more so than alp.
Analog drugs can be helpful for some but again, I don't recommend these. Dependence can build quickly or not at all. Some people are helped, some are. Some develop a cross tolerance, others don't. Too many variables. Clorazepate (Tranxene is an example here.)
As an interesting aside, some drugs prescribed for anxiety have some rather pleasant side effects on occasion. "Classical" benzos are usually great for off-label things. I was prescribed Chlordiazepoxide (Librium) for my anxiety for a short period and it helped me get back on my feet after a bout of SEVERE depression and OCD better than my SSRI ever hoped to. Not the same for everyone, obviously, but I foind it interesting. Librium can also help with a taper like diazepam but it's not nearly as well documented as the Ashton method so I wouldn't recommend that without a doctors help.
So anyway, yep. If you ever want to come off of benzos, ask your doctor about a diazepam or Librium taper, THANK YOU BIO FOR FIELDING THE QUESTIONS FOR ME! And yes, theres a chance your tolerance will raise switching. Not a lot but slightly. Not enough to let it stop you but enough so that you should keep close track to make sure you're not spiraling out of control. I suppose that's true in any scenario, though.
(05-25-2016, 12:57 AM)Bowser Wrote: Hey Raven and Jmoney12345,
Honestly, bio is absolutely correct for the most part except the complete disassociation between molecular makeup. I personally prefer diaz/alp and the only problem that presents is during one of my tapers (I've mentioned that either here or in another thread; I use the Ashton method to keep my tolerance low and have done so successfully for years). The semi regular switching between the two drives both tolerances up simultaneously thus making it a bitch to taper from diaz with diaz.
Theres always going to be an overlap in fill-in benzos and tolerance, particularly with the specific sub categories. If you take, say, triazoLAM then switch to alprazoLAM, there's going to be virtually identical tolerance raises. LorazePAM to clonazePAM will do the same. For an example, Xanax vs Klonopin. Xanax is a triazolo benzodiazepine. Klonopin is generally known as a plain old benzo, although it technically belongs to another sub family generally and informally called 7-nitro benzodiazepines. So there is some overlap when alternating those, yes, but not a lot. This is why a lot of doctors beginning treatment for GAD will prescribe alp/clon concurrently.
Long story short, there will be some tolerance crossover but not a whole hell of a lot.
There are other sub groups but I'm not totally familiar with but don't recommend like etizolam. That is a thienotriazolodiazepine and from what I understand extremely addictive when compared to most benzos, even more so than alp.
Analog drugs can be helpful for some but again, I don't recommend these. Dependence can build quickly or not at all. Some people are helped, some are. Some develop a cross tolerance, others don't. Too many variables. Clorazepate (Tranxene is an example here.)
As an interesting aside, some drugs prescribed for anxiety have some rather pleasant side effects on occasion. "Classical" benzos are usually great for off-label things. I was prescribed Chlordiazepoxide (Librium) for my anxiety for a short period and it helped me get back on my feet after a bout of SEVERE depression and OCD better than my SSRI ever hoped to. Not the same for everyone, obviously, but I foind it interesting. Librium can also help with a taper like diazepam but it's not nearly as well documented as the Ashton method so I wouldn't recommend that without a doctors help.
So anyway, yep. If you ever want to come off of benzos, ask your doctor about a diazepam or Librium taper, THANK YOU BIO FOR FIELDING THE QUESTIONS FOR ME! And yes, theres a chance your tolerance will raise switching. Not a lot but slightly. Not enough to let it stop you but enough so that you should keep close track to make sure you're not spiraling out of control. I suppose that's true in any scenario, though.
Oh, one last thing. Apologies for taking a while to respond, like I said I'm usually able to respond in less than 12 hours but yesterday was a 14 hour day so I didn't have much opportunity to get online. Thanks everyone!