pregabalin (Lyrica)

[invisiblejungle]

I agree that the media always blows things out of proportion, but I do have concerns regarding the gabapentinoids being over-prescribed (pregabalin, gabapentin, phenibut). I have experience with all 3 of these compounds, and I can definitely say that there is potential for physical addiction. They reduce glutamate and increase GABA by blocking voltage-gated calcium channels, and anything GABAergic can cause physical ddiction.

For some people, withdrawal from the gabapentinoids can be worse than withdrawal from benzos.